The biology of human longevity : (Record no. 26829)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03700nam a2200229Ia 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 250806s9999||||xx |||||||||||||| ||und|| |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780123736574 ;0123736579 |
| 060 ## - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | WT 116 |
| Item number | .F56 2007 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Finch, Caleb. |
| 245 #4 - TITLE STATEMENT | |
| Title | The biology of human longevity : |
| Remainder of title | inflammation, nutrition, and aging in the evolution of life spans / |
| Statement of responsibility, etc. | Caleb E. Finch. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Burlington, MA : |
| Name of publisher, distributor, etc. | Academic Press, |
| Date of publication, distribution, etc. | 2007 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xiii, 626 p. : |
| Other physical details | ill. (some col.) |
| Dimensions | 25 cm. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes bibliographical references (p. 417-599) and indexes. |
| 505 ## - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1. INFLAMMATION AND OXIDATION IN AGING AND CHRONIC DISEASES. 1.1. Overview ; 1.2. Experimental models for aging ; 1.3. Outline of inflammation ; 1.4. Bystander damage and dependent variables in senescence ; 1.5 Arterial aging and atherosclerosis ; 1.6. Alzheimer disease and vascular-related dementias ; 1.7. Inflammation in obesity ; 1.8. Processes of normal aging in the absence of specific diseases ; 1.9. Summary -- 2. INFECTIONS, INFLAMMOGENS, AND DRUGS. 2.1. Introduction ; 2.2. Vascular disease ; 2.3. Infections from the central tube : Metchnikoff revisited ; 2.4. Aerosols and dietary inflammogens ; 2.5. Infections, inflammation, and life span ; 2.6. Are infections a cause of obesity? ; 2.7. Inflammation, dementia, and cognitive decline ; 2.8. Immunosenescence and stem cells ; 2.9. Cancer, infection, and inflammation ; 2.10. Pharmacopleiotropies in vascular disease, dementia, and cancer ; 2.11. Summary -- 3. ENERGY BALANCE, INFLAMMATION, AND AGING. 3.1. Introduction ; 3.2. Diet restriction and aging ; 3.3. Energy sensing in diet restriction and satiety ; 3.4. Exercise, cardiovascular health, and longevity ; 3.5. Diet, exercise, and neurodegeneration ; 3.6. Laboratory rodents as models for the 'couch potato' ; 3.7. Energy balance in the life history ; 3.8. Summary -- 4. NUTRITION AND INFECTION IN THE DEVELOPMENTAL INFLUENCES ON AGING. 4.1. Introduction ; 4.2. Synopsis of the fetal origins theory ; 4.3. The Barker studies of infections and vascular disease ; 4.4. Size, health, and longevity ; 4.5. Infection and undernutrition on birthweight and later disease ; 4.6. Infection and nutrition in postnatal development and later disease ; 4.7. Famine ; 4.8. Maternal physiology, fetal growth, and later chronic disease ; 4.9. Growth in adaptive responses to the environment ; 4.10. Genomics of fetal growth regulation ; 4.11. Summary -- 5. GENETICS. 5.1. Introduction ; 5.2. Sources of individual variations in aging and life span ; 5.3. Sex differences in longevity ; 5.4. Metabolism and host-defense in worm and fly ; 5.5. The worm ; 5.6. Fly ; 5.7. Mammals ; 5.8. Summary -- 6. THE HUMAN LIFE SPAN : PRESENT, PAST, AND FUTURE. 6.1. Introduction ; 6.2. From great ape to human ; 6.3. Four major shifts in human life history from genetic and cultural evolution ; 6.4. The instability of life spans ; 6.5. Summary of chapters 1-6 : mechanisms in aging and life history evolution. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research, and expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections that may reverse the gains made in lowering inflammatory exposure.--BOOK JACKET. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aging |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Inflammation |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Longevity |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nutritional Physiological Phenomena |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| -- | DIMC |
| Koha item type | Books |
| Date last seen | Total checkouts | Full call number | Barcode | Price effective from | Koha item type | Lost status | Damaged status | Not for loan | Withdrawn status | Home library | Current library | Date acquired |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 08/06/2025 | WT 116 .F56 2007 | 00001580 | 08/06/2025 | Books | Dow International Medical College | Dow International Medical College | 08/06/2025 |