Molecular biology of cancer : mechanisms, targets, and therapeutics /
Lauren Pecorino.
- 2nd ed.
- Oxford ;;New York : Oxford University Press, c2008.
- xviii, 316 p. : ill.
Includes bibliographical references and index.
DNA structure and stability: mutations versus repair -- Regulation of gene expression -- Growth factor signaling and oncogenes -- The cell cycle -- Growth inhibition and tumor suppressor genes -- Apoptosis -- Stem cells and differentiation -- Metastasis -- Infections and inflammation -- Nutrients, hormones, and gene interactions -- The cancer industry: drug development and clinical trial design -- Cancer in the future: focus on diagnostics and immunotherapy.