Marks' essential medical biochemistry /
Michael Lieberman, Allan Marks, Colleen Smith.
- Philadelphia : Lippincott Williams & Wilkins, c2007.
- xiv, 565 p. : ill.
Based on Marks' basic medical biochemistry. 2nd ed. c2005.
Includes bibliographical references and indexes.
An overview of fuel metabolism -- Water, acids, bases, and buffers -- Structures of the major compounds of the body -- Amino acids and proteins -- Structure-function relationships in proteins -- Enzymes as catalysts -- Regulation of enzymes -- Cell structure and signaling by chemical messengers -- Structure of the nucleic acids -- Synthesis of DNA -- Transcription : synthesis of RNA -- Translation : synthesis of proteins -- Regulation of gene expression -- Use of recombinant DNA techniques in medicine -- Cellular bioenergetics: ATP and O??? -- Tricarboxylic acid cycle -- Oxidative phosphorylation, mitochondrial function, and oxygen radicals -- Generation of ATP from glucose : glycolysis -- Oxidation of fatty acids and ketone bodies -- Basic concepts in the regulation of fuel metabolism by insulin, glucagons and other hormones -- Digestion, absorption, and transport of carbohydrates -- Formation and degradation of glycogen --;Pathways of sugar and alcohol metabolism : fructose, galactose, pentose phosphate pathway, and ethanol metabolism -- Synthesis of glycosides, lactose, glycoproteins, glycolipids and proteoglycans -- Gluconeogenesis and maintenance of blood glucose levels -- Digestion and transport of dietary lipids -- Synthesis of fatty acids, triacylglycerols, eicosanoids, and the major membrane lipids -- Cholesterol absorption, synthesis, metabolism and fate -- Integration of carbohydrate and lipid metabolism -- Protein digestion and amino acid absorption -- Fate of amino acid nitrogen : urea cycle -- Synthesis and degradation of amino acids and amino acid derived products -- Tetrahydrofolate, vitamin B??????, and S-adenosylmethionine -- Purine and pyrimidine metabolism -- Intertissue relationships in the metabolism of amino acids.